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| IUPAC_Name: | 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide |
|---|---|
| InChI | InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19) |
| InChiKey | RJMUSRYZPJIFPJ-UHFFFAOYSA-N |
| Synonyms: |
Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy- 5-Chlor-N-(2-chlor-4-nitrophenyl)-2-hydroxybenzamid 5-Chloro-N-(2-chloro-4-nitrophényl)-2-hydroxybenzamide |
| Canonical SMILES: | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
| Physical Description: |
Solid PALE, YELLOW CRYSTALS：Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 1029 |
| Boiling Point: | 424.5±45.0 °C at 760 mmHg |
| Melting Point: | 225-230 DEG C |
| Flash Point: | 210.5±28.7 °C |
| Solubility: | SPARINGLY SOL IN CHLOROFORM, ETHER, ETHANOL |
| Stability: | TABLETS ARE SENSITIVE TO MOISTURE. |
| Density: | 1.6±0.1 g/cm3 |
| Vapour Pressure: | 0.0±1.0 mmHg at 25°C |
| Enthalpy of Vaporization: | 70.5±3.0 kJ/mol |
| Index of Refraction: | 1.709 |
| Molar Refractivity: | 79.0±0.3 cm3 |
| Experimental Gravity: | 210.5 g/mL |
| Experimental Flash Point: | 210.5 °C |
| Experimental Solubility: | DMSO <1 mg/mL; Water <1 mg/mL |
| Appearance: | yellow solid |
| Vapor Pressure: | <9.87X10-9 mm Hg at 20 deg C |
| Storage Conditions: | ... stored at a temp less than 30 deg C; freezing of the tablets should be avoided. |
| Taste: | Tasteless |
| Analytic Laboratory Methods: | Analysis of products: As in residue analysis ... or reduction with stannous chloride, reaction with p-dimethylaminobenzaldehyde, and determination of the intensity of the yellow dye at 460 nm (R Strufe, Pflanzenschutz-Nachr Bayer 1965, 18, 130-9); or redu |
| Drug Indication: | For the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used as a molluscicide in the control of schistosomiasis. |
| Safety: | GHS09 |
|---|---|
| GHS Classification: |   GHS Hazard Statements The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Precautionary Statement Codes P264, P273, P280, P305+P351+P338, P337+P313, P391, and P501 |
